منابع مشابه
Heterozygote Advantage for Fecundity
Heterozygote advantage, or overdominance, remains a popular and persuasive explanation for the maintenance of genetic variation in natural populations in the face of selection. However, despite being first proposed more than 80 years ago, there remain few examples that fit the criteria for heterozygote advantage, all of which are associated with disease resistance and are maintained only in the...
متن کاملHeterozygote advantage for the phenylketonuria allele.
Mean weight at birth of unaffected (normal homozygous and PKU heterozygous) offspring of parents heterozygous for the phenylketonuria (PKU) allele averages significantly above that of Norwegian neonates, with no significant difference in mean age of mothers or in mean parity. It approaches the optimal birthweight--that which confers the minimum overall mortality in the pre-, peri-, and postnata...
متن کاملNo Heterozygote Advantage in Fallow Deer
Effects of inbreeding on individual fitness are of long-standing interest in evolutionary biology and conservation studies. Since estimation of the inbreeding coefficient of a given individual is often impossible in wild populations, some authors have attempted to demonstrate inbreeding depression in such populations by correlating the multi-locus marker heterozygosity of individuals with a tra...
متن کاملHeterozygote advantage and the maintenance of polymorphism for multilocus traits.
Explaining how polymorphism is maintained in the face of selection remains a puzzle since selection tends to erode genetic variation. Provided an infinitely large unsubdivided population and no frequency-dependance of selective values, heterozygote advantage is the text book explanation for the maintenance of polymorphism when selection acts at a diallelic locus. Here, we investigate whether th...
متن کاملParasite-mediated heterozygote advantage in an outbred songbird population.
Coevolution with parasites is thought to maintain genetic diversity in host populations. However, while there are sound theoretical reasons to expect heterozygosity and parasite resistance to be related, this pattern has generally been shown only in inbred laboratory and island populations. This leaves doubt as to whether parasite-mediated selection for genetic diversity is in fact a general pr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2006
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0000125